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Cancer-related fatigue and its management.


Fatigue is the most common symptom found in the cancer patients, with a prevalence of more than 60%, as reported in the major part of various studies. This paper mainly reviews the management of the cancer related fatigue. In this paper, various pharmacologic agents are discussed for the management of fatigue in cancer patients and they comprise of psychostimulants, anti-depressants, corticosteroids, and hematopoietic agents. There are some other therapeutic agents such as paroxetine (serotonin reuptake inhibitors), bupropion, modafinil, and l-carnitine, but these agents are less studied for cancer related fatigue and at present, these agents are being focused in different clinical trials.

Key words: Cancer, fatigue, corticosteroids, anti-depressants, exercise.

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