Primary malignant bone tumors occur 1/100,000, of which 17-24% consists of chondrosarcoma. Unfortunately, the cause is unknown, but there have been several risks factors accused of causing the disease. Targeted therapy is a cancer specific treatment alternative to chemotherapy and radiation therapy. Its goal is to control and inhibit cancer promoting pathways as well as activating patient's own immune system to fight the tumor. The patient's immune system is stimulated by exposing synthetic immune molecules into their system. In this paper, we discuss the potential causes of chondrosarcomas, the pathophysiology of the disease, and potential ways to cure the disease using different targeted therapy techniques.
Key words: Bone cancer, chondrosarcoma, targeted therapy, TKIs, mTOR inhibitorsDownload Pdf